One in eight U.S. women will develop invasive breast cancer in their lifetime. The treatment of invasive breast cancer should be personalized because what is best for one woman may not be right for another. If you have breast cancer, it's important to take an active role in your health by learning about your available treatment options. An ongoing, collaborative discussion with your doctor is key in determining what treatment option best fits your individual needs.
(BPT) - As a commercial airline pilot with nearly 30 years of experience, Diane Sandoval, 50, is no stranger to making difficult decisions. However, she faced one of her toughest challenges not in the skies, but when she discovered a small lump in her left breast during a self-examination. Her worst fear was confirmed after a visit to her doctor when she was diagnosed with early-stage breast cancer.
Following an inconclusive mammogram and ultrasound, Sandoval learned she had several small tumors. She underwent a mastectomy to remove the tumors followed by breast reconstruction, putting her piloting career on pause.
The next big question was whether she should receive chemotherapy or not. Her physician recommended a genomic test — the Oncotype DX Breast Recurrence Score test. This tool has been proven to determine whether chemotherapy will be beneficial for individuals recently diagnosed with early-stage breast cancer. The test provides a personalized score based on the biology of the patient’s tumor that can help tailor treatment decisions for their individual cancer. Recent results from the largest breast cancer study ever conducted, called TAILORx, confirmed that the test clearly identified the 70 percent of women with early-stage breast cancer who receive no benefit from chemotherapy, as well as the remaining 30 percent of women for whom chemotherapy can be life-saving.
Sandoval is one of the nearly 1 million women who has put chemotherapy to the test with this genomic test. Her score confirmed that her risk of experiencing a breast cancer recurrence was low and she would not benefit from chemotherapy. As a result, she felt confident that she could forgo chemotherapy and its associated side effects. Subsequently, she was able to resume her career as a pilot and her active lifestyle.
She recently joined a campaign called “Put Chemo to the Test” to raise awareness of the Oncotype DX test and encourage women recently diagnosed with early-stage breast cancer to ask their doctor to order it before finalizing their treatment plan.
“I hope to help women with early-stage breast cancer better understand their treatment options by raising awareness of this test and how it can determine whether they are part of the majority of patients who may be spared chemotherapy and its well-known side effects or are among the important minority of patients who could receive life-saving benefit from chemotherapy,” said Sandoval.
One in eight U.S. women will develop invasive breast cancer in their lifetime. The treatment of invasive breast cancer should be personalized because what is best for one woman may not be right for another. If you have breast cancer, it's important to take an active role in your health by learning about your available treatment options. An ongoing, collaborative discussion with your doctor is key in determining what treatment option best fits your individual needs. Below are a few questions to ask your doctor:
Breast cancer patients and caregivers can visit ChemoYesorNo.org to download the full physician discussion guide and learn more about the test.
“I want women who were recently diagnosed with early-stage breast cancer to know that there is no one-size-fits-all treatment approach,” said Sandoval. “The test gave me the confidence I needed to forgo chemotherapy, which has allowed me to continue to enjoy my life with my husband. Ask your doctor to order this genomic test before finalizing your treatment plan.”
Over the past 10 years, researchers have learned Alzheimer’s disease starts much earlier than the onset of symptoms – 10-20 years before an individual, family member or friend might notice the signs of the debilitating disease. Researchers are looking for a diverse group of people ages 50 or older who have normal thinking and memory function.
How the Internet Can Help Prevent Alzheimer’s Disease
(Family Features) Over the past 10 years, researchers have learned Alzheimer’s disease starts much earlier than the onset of symptoms – 10-20 years before an individual, family member or friend might notice the signs of the debilitating disease.
According to the Alzheimer’s Association, 5.5 million Americans, of all races and ethnicities, age 65 and older currently live with Alzheimer’s disease, which is expected to grow to more than 7 million people by 2025.
The first-of-its-kind Alzheimer Prevention Trials Webstudy (APT Webstudy), funded by the National Institutes of Health, aims to increase the pace of research by enlisting thousands of healthy volunteers who can quickly be enrolled in clinical trials focused on preventing Alzheimer’s disease. Enrollees in the APT Webstudy can use the internet to help stop the disease while being alerted to changes in their own memory function.
“In order to change the lives of the numerous people and their loved ones who will be affected by Alzheimer’s, we need everyone to get involved with prevention efforts,” said Paul Aisen, MD, co-principal investigator of the APT Webstudy. “The bigger the army of volunteers, the faster we can work to prevent this terrible disease.”
Volunteers can access the Webstudy when and where it is convenient for them, such as on their computer or tablet, or even a public library; anywhere they can access the internet. Volunteers participate in regular online memory testing. If there is a change in memory function, eligible volunteers are alerted and may be invited to a no-cost, in-person evaluation at one of the research sites across the country.
“This is an opportunity for everyone to help future generations avoid the suffering caused by Alzheimer’s,” Aisen said. “With enough volunteers, we will be one step closer to seeing the first Alzheimer’s survivor.”
Researchers are looking for a diverse group of people ages 50 or older who have normal thinking and memory function. Volunteers must be willing to answer a few questions about their family and medical history and provide information about their lifestyles. Volunteers will take online memory tests every three months, each one about 20 minutes long.
If you are interested in participating, visit aptwebstudy.org to learn more.
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Alzheimer’s Prevention Trials
A study funded by the National Institutes of Health is testing whether the nicotine patch can improve memory and functioning in people who have mild memory loss or Mild Cognitive Impairment (MCI).
Nicotine to Help Treat Memory Loss?
(Family Features) A study funded by the National Institutes of Health is testing whether the nicotine patch can improve memory and functioning in people who have mild memory loss or Mild Cognitive Impairment (MCI).
The largest and longest running study of its kind, the MIND (Memory Improvement through Nicotine Dosing) Study is looking for 300 volunteers at sites across the United States who have mild memory loss but are otherwise healthy, non-smokers over the age of 55.
“The MIND Study will provide valuable information for researchers with regard to early memory loss that is associated with normal aging and early Alzheimer’s disease, but we need volunteers if we are going to succeed,” said Dr. Paul Newhouse, MD, director of the Vanderbilt Center for Cognitive Medicine and lead investigator for the MIND Study.
According to the Alzheimer’s Association, approximately one in five people age 65 or older have mild memory loss or MCI and are more likely to develop Alzheimer’s disease or other dementias. Currently, there is no FDA-approved medication indicated to treat this condition; however, nicotine stimulates an area in the brain known to be important for thinking and memory, and scientists believe it could be an effective treatment for adults with MCI.
“People often think nicotine is addictive and harmful because it is in tobacco products, but it’s safe when used in patch form,” Newhouse said. “Nicotine is an inexpensive, readily available treatment that could have significant benefits for people experiencing mild memory impairment.”
The MIND Study needs 300 people to enroll in sites across the United States. Researchers are looking for healthy, non-smoking adults over the age of 55 who are in the earliest stages of memory loss to participate in the MIND Study.
Potential study volunteers can learn more by visiting MINDStudy.org or calling 1-866-MIND-150.
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Memory Improvement through Nicotine Dosing (MIND)
While researchers are still unraveling exactly how probiotics accomplish all that they do, it’s understood that probiotics help establish a healthy environment in your digestive tract. Now, you can get your probiotics from many of your favorite foods and drinks without taking pills with some surprising products that include probiotics.
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